Department Calendar of Events

Oct
18
Wed
LLE – Curvature Directed Assembly of Colloids at Interfaces @ WB 116
Oct 18 @ 12:00 pm

Lectures at the Leading Edge

“Curvature Directed Assembly of Colloids at Interfaces”

Kathleen Stebe, University of Pennsylvania

Oct
23
Mon
BioZone Mass Spectrometry Facility: User Meeting @ Wallberg Building, Room 219 (2nd floor)
Oct 23 @ 9:00 am – 2:00 pm

Join BioZone to learn about and discuss the latest advancements in Mass Spectrometry technology. Topics include:

  • New developments in mass spectrometry analysis
  • Using mass spectrometry to support research
  • Starting material requirements, sample prep, and protocol development

Click here for your ticket.

Oct
26
Thu
IWI Seminar: Affluence from effluents: safe disposal, reuse, and energy harnessing from sewage and biosolids @ Wallberg WB215
Oct 26 @ 2:00 pm – 3:00 pm

Affluence from Effluents: Safe Disposal, Reuse, and Energy Harnessing from Sewage and Biosolids

FAISAL HAI, University of Wollongong

This presentation will provide snapshots of current research focus of the Environmental Biotechnology Laboratory led by Dr. Hai at the University of Wollongong, Australia. Our work underpins the protection of land and water resources from contamination and focuses on the aspects of wastewater treatment and reuse, management of biosolids originating from wastewater treatment plants, and providing environmental solutions for resource and energy development projects.

This presentation will particularly focus on:
Next generation membrane bioreactors (MBRs): high retention MBRs (nanofiltration/ reverse osmosis/ forward osmosis membranes integrated with biological reactors) and enzymatic membrane bioreactors for removal of contaminants of emerging concern e.g., endocrine disruptors. Resource recovery from waste: membrane assisted phosphorus and methane recovery from wastewater/sludge, and enzymatic bioethanol production from solid waste.

FAISAL I. HAI is an Associate Professor at the School of Civil, Mining and Environmental Engineering (CME) of the University of Wollongong (UOW), Australia. He is one of the key teaching and research academics of the Strategic Water Infrastructure Laboratory at CME. A recipient of Japan Society for Promotion of Science fellowship (2007- 2009) and UOW Vice Chancellor’s fellowship (2010), Dr. Hai was awarded the outstanding lecturer award by the Japanese Society on Water Environment in 2010, and UOW Vice Chancellor’s Outstanding Contribution to Teaching and Learning Award in 2015. Building on his vast experience of working with Professor Kazuo Yamamoto, the inventor of the membrane bioreactor (MBR) technology, at the University of Tokyo, he continues to carry out exciting research on the application of hybrid membrane processes for the removal of biologically persistent compounds (especially micropollutants) from water and wastewater. Dr. Hai is the lead editor of a recent book, Membrane Biological Reactors, published by the International Water Association. Dr. Hai also serves as an Associate Editor of the renowned journal, Water Science & Technology (IWA Publishing, UK) and Journal of Water and Environment Technology (Japan Society on Water Environment).

Nov
1
Wed
SOCAAR Seminar Series: Hui Peng, University of Toronto, Department of Chemistry: Oxidative Stress: a Merged Toxic Pathway for Environmental Matrices @ Wallberg Building WB407
Nov 1 @ 3:00 pm – 4:00 pm

Oxidative stress has been suggested to be the primary toxic pathway of air particulate matter (PM) to cause cardiovascular disease and other adverse effects. In this talk, oxidative stress was demonstrated as the primary toxic pathway for both disinfection by-products (DBPs) in drinking water, and oil sands-processed water (OPSW). To this end, a hybrid platform was established in our group to identify toxic components and their modes of action (MOA) from these critical environmental matrices. High-throughput and reproducible in vitro cell reporter system was used to determine the Nrf2-mediated oxidative stress response from environmental mixtures. Then, Effect-Directed Analysis (EDA) and chemical probe, combined with untargeted chemical analysis, were used accordingly to identify toxic components. Specifically, more than 600 DBPs were identified in the drinking water after disinfection and direct reaction with cysteine was elucidated as the primary pathway for DBPs to cause oxidative stress. Accordingly, a biotin/cysteine chemical probe was synthesized to identify toxic DBPs. For OSPW whose oxidative stress may primarily be caused by indirect pathways, EDA combined with untargeted chemical analysis was used to identify hydroxylated aldehydes as the primary toxic components. Studies regarding PM samples are still ongoing, and preliminary data shown that chemical probe is an efficient approach to identify toxic components (i.e. quinone) in PM samples. Thus, our hybrid platform may provide a versatile and accessible approach in elucidating the oxidative stress promoting components in a variety of environmental matrices.

DETAILS: Uoft.me/SOCAAR1NOV17

Nov
3
Fri
Guest Lecture: Design of bioswitches and cellular robots for metabolic engineering and synthetic biology @ Wallberg WB215
Nov 3 @ 10:00 am – 11:00 am

Design of bioswitches and cellular robots for metabolic engineering and synthetic biology

Professor An-Ping Zeng,
Institute of Bioprocess and Biosystems Engineering,
Hamburg University of Technology

Despite impressive progresses in systems metabolic engineering and synthetic biology there are still several unsolved major problems in their practical applications for developing effective metabolic pathways and microorganisms for biosynthesis, including:

  1. identification of targets for advanced pathway engineering of productive strains, especially under industrially relevant and in vivo conditions;
  2. effective means with proper dynamic range and sensitivity for dynamic and concerted control of metabolic pathways;
  3. designed elements or devices from synthetic biology often not work well within the host cells, especially for highly productive strains;
  4. mathematical models of cellular processes often miss regulatory details inside cells and thus fail to guide biomolecular and cellular design.

In this presentation, I will illustrate some of our recent efforts to address these questions. First, I will present results on rational design of bioswitches (riboswitch and ligand-introduced allosteric regulation) with improved dynamic range and sensitivity for dynamic control of metabolic pathways. Then, I will address the question how we can use the host cell as “a computer or robot” to identify targets, evaluate designed parts and even to evolve the best design for a specific purpose? Cells are capable of information processing, rapid replication and performing tasks adaptively and ultra-sensitively. The key issue is how to let the cells “to compute or evaluate” the processes we are interested in and how “to output” the right results corresponding to the different inputs? To this end, we have used E. coli as an example to rein the computation abilities of cells by designing high throughput input and sensitive output systems based on its interaction with bacteriophage. The method is successfully demonstrated for target identification, evaluation of designs, evolution and selection of key enzymes for lysine bioproduction in E. coli.

Nov
22
Wed
LLE – Optimising Structure-Property Dependencies of Stochastic Materials by Probabilistic Modelling @ WB 116
Nov 22 @ 12:00 pm

Lectures at the Leading Edge

“Optimising Structure-Property Dependencies of Stochastic Materials by Probabilistic Modelling”

William Sampson, University of Manchester

Nov
23
Thu
ChemE 4th Year Capstone Plant Design Presentations @ Wallberg Building and Bahen Centre, St. George Campus
Nov 23 – Nov 30 all-day

ChemE’s Plant Design presentations start TODAY! ALL are welcome to attend

Plant Design is our fourth-year capstone design course where students work in teams to create a preliminary design for a chemical plant, including generating a detailed economic analysis. The course brings together everything they’ve learned throughout their undergraduate education.

Presentations are held in the Wallberg Building (WB) and the Bahen Centre (BA), both located on the St. George Campus.

Check out the schedule for details: https://tinyurl.com/capstonedesign2017

Dec
6
Wed
LLE – Megasupramolecules @ WB 116
Dec 6 @ 12:00 pm

Lectures at the Leading Edge

“Megasupramolecules”

Julia Kornfield, California Institute of Technology

SOCAAR Seminar Series: Dr. Kelly Sabaliauskas (Toronto Public Health) @ Wallberg Building WB407
Dec 6 @ 3:00 pm – 4:00 pm

Extreme heat is a significant health risk for a large proportion of Toronto’s population. Heat-vulnerable groups include children, older adults, people who are socially isolated or have low incomes, including those who are experiencing homelessness. Toronto Public Health estimates that extreme heat contributes to an average of 120 deaths per year in Toronto and that could increase with climate change. This presentation will highlight work that Toronto Public Health is undertaking to help address the risks of extreme heat including climate forecasting, heat vulnerability mapping, population surveillance, hot weather response and community outreach. Policy opportunities and data needs will also be discussed.

Jan
10
Wed
LLE – CO2-Switchable Materials @ WB 116
Jan 10 @ 12:00 pm

Lectures at the Leading Edge

“CO2-Switchable Materials”

Philip Jessop, Queen’s University

Industrial inefficiencies, causing wastage of energy and materials, are often the result of failures to resolve time-separated conflicting requirements. For example, a drying agent particle must to strongly absorb water from something that needs to be dried, but must easily release the water when the drying agent is being regenerated. Switchable materials can solve such problems. Waste CO2 is a renewable material that can be used to reversibly trigger changes in the properties of liquids, solutes, or surfaces. This presentation will portray two different classes of switchable materials, a class of switchable solvents and a series of switchable surfaces, and discuss how their design and use can help solve practical problems (e.g.water purification, paints and coatings) while reducing environmental impact.