Department Calendar of Events

Jun
22
Fri
Development of Self-healing Coatings Based on Microcapsules Filled with Active Agents @ WB407
Jun 22 @ 11:00 am – 12:00 pm

In this presentation, an overview of recent advances in self-healing coatings is provided. The talk focuses on the microencapsulation of active compounds used mainly in the polymer coatings. Various preparation methods of microcapsules and their advantages and shortcomings will be discussed. In addition, some recent activities in my research group relate to the preparation of ethyl cellulose (EC), urea-formaldehyde (UF), and polyurethane (PU) microcapsules will be described. Self-healing performance of these microcapsules for enhancing the mechanical properties, barrier performance and corrosion resistance of coatings will be presented.


Mojtaba Mirabedini is a University Professor at the Iran Polymer and Petrochemical Institute (IPPI) and head of Color and Surface Coatings Department.  He is recently invited as a visiting Professor at the Eastern Michigan University. Dr. Mirabedini received his PhD in Corrosion Protection Coatings from the University of Manchester (UMIST) in 2000, working under supervision of late Professor David Scantlebury and Proferssor George Thompson. He specializes in smart polymeric coatings, nanocomposites coatings and adhesives. His current research focuses on developing novel smart functional coatings, self-healing coatings, thread locking adhesives, self-cleaning coatings, and advanced pavement markings. Dr. Mirabedini has been collaborating with Prof. Farnood on the microencapsulation of active materials for smart coating applications since 2010.

Jun
24
Sun
Engineering Gateways: Communicating for Success as Women in Engineering @ Bahen Centre
Jun 24 @ 1:00 pm – 3:00 pm

Join IEEE Canada Women in Engineering (WIE) and IEEE Toronto WIE Group for the “Engineering Gateways: Communicating for Success as Women in Engineering” Panel at the IEEE Professional Communication 2018 (ProComm’18). Diverse perspectives will be brought to this panel on topics such as communications, self-promotion, professional branding, and strategies for intervention.

Speakers:
Namir Anani
President and CEO of Information and Communications Technology Council

Christine Laperriere
Lead Coach and Executive Director of the Women of Influence Advancement Centre

Teresa Sing
VP Business Development, Refine Recruitment

Jennifer van Amerom
Founder and CEO, Refine Recruitment

Deborah-Tihanyi
Associate Professor, Teaching Stream, Director, and Communication Coordinator
University of Toronto

Jun
26
Tue
Special Lecture: COSMO-RS, the currently most accurate solvation model and its applications in chemical engineering, chemistry and formulation science @ WB215
Jun 26 @ 4:00 pm

Prof. Dr. Andreas Klamt, COSMOlogic, GmbH & Co KG, & Institute of Physical and Theoretical Chemistry, University of Regensburg

COSMO-RS is an alternative approach to the a priori prediction of chemical potentials, activity coefficients and vapor pressures of almost arbitrary chemical compounds in pure liquid solvents and mixtures. In contrast to the group contribution methods COSMO-RS gets the information about the intermolecular interactions from uni-molecular quantum chemical calculations on the compounds and thus it is far less dependent on experimental data. Hence COSMO-RS is an efficient alternative to group contribution methods on the one hand and to the Monte-Carlo and Molecular Dynamics simulations on the other hand. Aside from a few disadvantages it has a lot of systematic advantages. The greatest strengths are the broad applicability and extrapolation power of the method, and the systematic physical insight into the mixture behavior of the systems, which COSMO-RS opens by its sound physical basis. Thus, complicated or rare compounds can be treated and differences between isomers can be resolved. Different comparisons and blind test challenges proofed that COSMO-RS currently provides the most accurate predictions for free energies of molecules in solution.

Beyond the basic features regarding activity coefficients, vapor pressures, and enthalpies of fluid systems, COSMO-RS can be applied to solid-liquid equilibria, to solubility in polymers, to ionic liquids and electrolytes, to pKa-prediction, to adsorption phenomena and physiological partitioning, reaction thermodynamics, micelle and biomembrane binding, chromatographic retention times, co-crystal formation probabilities, and many other problems in chemical engineering, chemistry and formulation.

COSMOplex, a brand-new extension of COSMO-RS to the self-consistent simulation of inhomogeneous, self-organizing systems, will be presented as well. It enables many the simulation of molecules at liquid-liquid interfaces, of micelle formation an even of microemulsions at simulation times 10000 times smaller than required by MD simulations.


Dr. Andreas Klamt studied physics in Göttingen and received his first degree in 1984 in theoretical metal physics. Then he moved on to the Max-Planck-Institut for Metal Research in Stuttgart, where he received his PhD in 1987 with a thesis on ‘States of small positively charged particles in metals’

Then he directly started to work at Bayer AG in Leverkusen in the area of Computational Chemistry. He specialized on solvation and physical property prediction and developed the methods COSMO and COSMO-RS which meanwhile are widely used in the computational chemistry community. After being head of the central department for Computational Chemistry at Bayer for 3 years, he left Bayer in 1999 and founded COSMOlogic GmbH&Co.KG, Leverkusen, a company for Computational Chemistry and Fluid Phase Thermodynamics, Software and Consulting, which now has 17 co-workers.

In 2005 he received his habilitation in Physical Chemistry at University of Regensburg, and in since 2012  he is honary professor, teaching courses for “Computational Fluid Phase Thermodynamics”  every October in Regensburg.

Jul
11
Wed
Seminar: Repairing and Regenerating Brain Tissue after a Stroke @ Donnelly Centre, Red Seminar Room (2nd Floor)
Jul 11 @ 11:00 am – 12:00 pm

Dr. Mike Modo,
Department of Radiology, University of Pittsburgh

The brain is considered to only have a limited capacity to repair damaged tissue and entirely lack the potential to regenerate lost tissue. Tissue lost after a stroke is therefore not spontaneously replaced and create a cystic cavity filled with extracellular fluid. To repair tissue damage in the peri-infarct area, we are pursuing the use of fetal-derived human neural stem cells for implantation to enhance the ongoing endogenous repair process. Although this approach has found its clinical translation, the procedure still requires optimization to ensure an appropriate delivery of cells into different tissue microenvironment. Enhancing cell survival and integration using instructive biomaterials and rehabilitation strategies are investigate to inform future clinical trials and ensure therapeutic efficacy. However, this approach does not lead to a regeneration of tissue inside the stroke cavity. To promote the invasion of endogenous brain cells into this tissue void, we are therefore investigating the implantation of inductive bioscaffolds formed out of extracellular matrix. These hydrogels attract host cells and can be efficient degraded while bridging the tissue gap. We therefore propose that this approach can induce regeneration of brain tissue in the stroke cavity. It is hope that these regenerative medicine approach will provide new therapeutic horizons for patients with stroke.

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Mike Modo, a Luxembourg-native, graduated in Psychology from Royal Holloway University of London (1997), UK, and spend 1 year as an undergraduate at the Psychology Department at McGill University (1995-1996) in Montreal, Canada. He then furthered his interests in the neural correlates underlying behavioral functions during an M.Sc. in Neuroscience (1998) at the Institute of Psychiatry at King’s College London, where he also continued his research efforts leading to a PhD in Neurosciences (2001). The main interest of Dr Modo’s research lies in the restorative neurobiology following brain damage, predominantly focused on stroke, but also in Parkinson’s and Huntington’s disease. An interdisciplinary approach is espoused that involves the use of pharmacological agents, stem cells, as well as biomaterials. A special focus lies on the development of magnetic resonance imaging (MRI) methods that allow us to guide and monitor in situ tissue engineering. Our ultimate aim is to restore a functional tissue in the brain that can support behavioral recovery.

 

Hosted by Dr. Molly Shoichet
Snacks and Refreshments will be served

Aug
14
Tue
UnERD 2018 Conference Day @ Bahen Centre
Aug 14 all-day

UnERD is the largest undergraduate research competition at the University of Toronto. It is the perfect conference for you to showcase your findings and accomplishments to like-minded students and professors. Attendees will have the chance to learn about research being done in the community and discover the opportunities available to undergraduate students.

Click HERE or important dates and details

Sep
21
Fri
Guest Lecture: Online laser monitoring of metal chloride and oxygen concentration using collinear photofragmentation and atomic absorption spectroscopy @ WB215
Sep 21 @ 3:10 pm

Jan Viljanen
PhD Candidate in Applied Optics
Tampere University of Technology, Finland

Collinear photofragmentation and atomic absorption spectroscopy (CPFAAS) is a recently developed optical method for analysing molecular concentrations and their kinetics. [1,2] The technique is based on the fragmentation of a precursor molecule and the detection of the fragment atoms via absorption spectroscopy on a common laser beam path. It has been applied to monitor concentrations of the precursors KCl and KOH in thermal conversion applications. CPFAAS studies have focused on precursor molecule concentration analysis using the maximum absorbance right after the photofragmentation. Sample lengths ranging from 1 cm to 10 m have been demonstrated in the studies [2,3]. In this work, an overview and recent development of CPFAAS is presented.

Typical CPFAAS measurement arrangement is shown in Fig 1. CPFAAS technique has been demonstrated for online monitoring of KCl, KOH, and O2 in a single particle reactor [2,3] and for KCl and PbCl2 in full-scale power plant. Typical molecular detection limits reach sub-ppm levels. The spatial resolution of the measurement can be adjusted by tuning the overlapping of the fragmenting and probing laser beams. This allows collection of localized information that is often required to support modelling work of flames and combustion processes. Online measurement of PbCl2 is a powerful demonstration of the CPFAAS technique’s ability to be applied also to monitoring of more complex molecules, such as ZnCl2, that are present in combustion processes. In addition, recent development in laser sources has brought NaCl and NaOH monitoring closer to realization.

________________________________

Jan Viljanen is finalizing his PhD in the Applied Optics research group at Tampere University of Technology, Finland. Jan has previously worked with Professor Nikolai DeMartini on the application of the techniques discussed in this talk to the release of K compounds in burning biomass particles. If you would like to meet with Jan individually, he will be available from 1 – 2:30 pm on Friday, September 21st. Please contact Professor DeMartini for details.

 

To download the lecture abstract, click HERE

Sep
28
Fri
BioZone Horizons Symposium @ Wilson Hall Rm.1017
Sep 28 @ 9:00 am – 6:00 pm

Join us for a day of presentations where members from industry and academia share their knowledge and experiences, including a poster presentation session for students to explain the potential industrial impact of their work.

Guests include:

  • Dr. Pratish Gawand
    Co-founder, CEO, Ardra Bio Inc.
  • Dr. Yaldah Azimi
    Water Design Specialist, CH2M-Jacobs
  • Dr. Scott Genin
    Head of Materials Discovery, OTI Lumionics

 

Lunch provided.

Oct
5
Fri
Special Seminar: Molecular Understanding, Design and Development of Ultra-low Fouling Zwitterionic Materials @ Donnelly Centre, Red Seminar Room (2nd Floor)
Oct 5 @ 11:00 am – 12:30 pm

Dr. Shaoyi Jiang
Department of Chemical Engineering,
University of Washington

An important challenge in many applications, ranging from drug delivery carriers to medical devices, is the prevention of nonspecific protein adsorption on surfaces. To address this challenge, our goals are twofold. First, we strive to provide a fundamental understanding of nonfouling mechanisms at the molecular level. Second, we aim to develop biocompatible and environmentally benign ultra low fouling materials based on the molecular principles we have learned. Over the last 15 years, we have demonstrated that zwitterionic and mixed charge materials and surfaces are highly resistant to nonspecific protein adsorption, cell adhesion and bacteria adhesion/biofilm formation from complex media. Both simulation and experimental results indicate that the strong hydration of zwitterionic materials is responsible for their excellent nonfouling properties. Recent results show that zwitterionic materials do not induce immunological response in blood circulation and capsule formation upon implantation and are able to preserve protein and cell bioactivity. Zwitterionic materials have been shown to be superior to poly(ethylene glycol) (PEG)-based materials for a number of biomedical and engineering applications such as drug delivery carriers, medical devices, cell preservation/expansion media, and marine coatings.
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Professor Shaoyi Jiang received his Ph.D. degree in chemical engineering from Cornell University in 1993. He was a postdoctoral fellow at the University of California, Berkeley between 1993 and 1994 and a research fellow at California Institute of Technology between 1994 and 1996 both in chemistry. He is currently the Boeing-Roundhill Professor in the Department of Chemical Engineering and an adjunct professor of Bioengineering at the University of Washington, Seattle. He was a visiting professor in the Department of Chemical Engineering at MIT with Prof. Robert Langer in 2007. He is a senior editor for Langmuir, a fellow of the American Institute of Chemical Engineers (AIChE), a fellow of the American Institute for Medical and Biological Engineering (AIMBE) and a member of Washington Academy of Sciences. He received the Braskem Award for Excellence in Materials Engineering and Science, AIChE (2017). His research focuses on the molecular understanding, design and development of zwitterionic-based functional materials for biomedical and engineering applications.

 

Hosted by Dr. Molly Shoichet
Snacks and Refreshments will be served

 

Oct
15
Mon
The Problem with Persistence: PFAS as Extreme Emerging Water Contaminant @ Sanford Fleming SF3201
Oct 15 @ 4:10 pm

Dr. Carla Ng
Departments of Civil & Environmental Engineering, & Chemical & Petroleum Engineering
UNIVERSITY OF PITTSBURGH

Per and polyfluorinated alkyl substances (PFAS) comprise a large group of industrial chemicals that have become pervasive environmental contaminants. Among them, long-chain perfluorinated alkyl acids are now recognized as extremely persistent, bioavailable, and bioaccumulative substances. Growing concern regarding their toxicological effects has led to (largely voluntary) phaseouts in the US and Europe. Short-chain acids were suggested as immediate drop-in replacements because they do not bioaccumulate and are therefore considered less toxic. Yet emerging data on the potential toxicity of even very low levels of certain PFAS is driving regional “action levels” in drinking water in the part per trillion range.

At the same time, a wide variety of “alternative PFAS” have increased production to fill market demand. Thousands of different PFAS, with a variety of chain lengths, degrees of fluorination, and functional groups are now used in industries ranging from fire fighting to industrial processing to personal care products to food packaging. Very little is known about the bioaccumulation potential and toxic effects of these replacement compounds.

In this seminar, we will explore why current risk assessment paradigms and water treatment approaches fail to adequately capture or mitigate the risks posed by PFAS and discuss strategies for addressing this pressing global contamination problem.

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Dr. Carla Ng is an Assistant Professor in Civil and Environmental Engineering at the University of Pittsburgh, with a secondary appointment in Chemical & Petroleum Engineering.  She received her PhD in Chemical & Biological Engineering from Northwestern University in 2008. The research in Dr. Ng’s group focuses on the development of models for the fate of chemicals in organisms and ecosystems, at the intersection of chemistry, biology and engineering. Active research areas include the development of mechanistic models for the bioaccumulation of emerging contaminants in organisms, tracking the fate of legacy and current-use pesticides in tropical environments, and exploring the role of the industrial food system on the fate of environmental contaminants, with implications for human exposure.

Oct
17
Wed
LLE: Irving O. Shoichet Distinguished Lecture | Giving New Life to Materials for Energy, the Environment, and Medicine @ Wallberg WB116
Oct 17 @ 12:00 pm – 1:00 pm


ANGELA BELCHER

Massachusetts Institute of Technology

Giving New Life to Materials for Energy, the Environment, and Medicine 

Organisms have been making exquisite inorganic materials for over 500 million years. Although these materials have many desired physical properties such as strength, regularity, and environmentally benign processing, the types of materials that organisms have evolved to work with are limited. However, there are many properties of living systems that could be potentially harnessed by researchers to make advanced technologies that are smarter, more adaptable, and that are synthesized to be compatible with the environment. One approach to designing future technologies which have some of the properties that living organisms use so well, is to evolve organisms to work with a more diverse set of building blocks. The goal is to have a DNA sequence that codes for the synthesis and assembly of any inorganic material or device. We have been successful in using evolutionarily selected peptides to control physical properties of nanocrystals and subsequently use molecular recognition and self-assembly to design biological hybrid multidimensional materials. These materials could be designed to address many scientific and technological problems in electronics, environmental remediation, medicine, and energy applications. Currently we are using this technology to design new methods for building batteries, fuel cells, solar cells, carbon sequestration and storage, environmental remediation, catalysis, and medical diagnostics and imaging. This talk will address conditions under which organisms first evolved to make materials and scientific approaches to move beyond naturally evolved materials to genetically imprint advanced technologies with examples in lithium and sodium ion batteries, lithium-air batteries, environmental clean-up and ovarian cancer imaging and treatment.
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Angela Belcher is a biological and materials engineer with expertise in biomaterials, biomolecular materials, organic-inorganic interfaces and solid-state chemistry and devices. Her primary research focus is evolving new materials for energy, electronics, the environment, and medicine. She received her B.S. in Creative Studies from The University of California, Santa Barbara. She earned a Ph.D. in inorganic chemistry at UCSB. Following with her postdoctoral research in electrical engineering at UCSB. She now holds the James Mason Crafts Professor of Biological Engineering and Materials Engineering at MIT. She is faculty in the Department of Biological Engineering, Materials Science and Engineering and the Koch Institute of Integrative Cancer Research. She teaches undergraduate subjects in material sciences and engineering and biological engineering. In 2002, she founded the company Cambrios Technologies, Inc., and in 2007 she founded Siluria Technologies, Inc. Some recent awards include the 2013 $500,000 Lemelson-MIT Prize for her Inventions, 2010 Eni Prize for Renewable and Non-conventional Energy, in 2009 Rolling Stone Magazine listed her as one of the top 100 people changing the country. In 2007, Time Magazine named her a “Hero”- for her research related to Climate Change. In 2004, she received the Four Star General Recognition Award (US Army) for significant contribution to army transformation. In 2000, she was awarded the Presidential Early Career Award in Science and Engineering (PECASE). She was named Research Leader of the Year by Scientific American, and is a MacArthur Fellow, a Packard Fellow, a NAI (National Academy of Inventors) Fellow, an Alfred P. Sloan Fellow, a NAE (National Acedemy of Engineers) Fellow, and a member of American Academy of Arts and Sciences.

 

Download the lecture poster HERE

For more information on Lectures at the Leading Edge 2018-19 click HERE.